Lipid Composition of Purified Vesicular Stomatitis Viruses
نویسندگان
چکیده
منابع مشابه
Transmission and pathogenesis of vesicular stomatitis viruses
Vesicular Stomatitis (VS) is caused by Vesicular stomatitis viruses (VSV), negative single stranded RNA arthropod-borne members of the Family Rhabdoviridae. The VSV virion is composed of the host derived plasma membrane, the envelope, and an internal ribonucleoprotein core. The envelope contains a transmembrane glycoprotein, the G protein, which mediates viral entry and exit from the cell. The ...
متن کاملAttenuated vesicular stomatitis viruses as vaccine vectors.
We showed previously that a single intranasal vaccination of mice with a recombinant vesicular stomatitis virus (VSV) expressing an influenza virus hemagglutinin (HA) protein provided complete protection from lethal challenge with influenza virus (A. Roberts, E. Kretzschmar, A. S. Perkins, J. Forman, R. Price, L. Buonocore, Y. Kawaoka, and J. K. Rose, J. Virol. 72:4704-4711, 1998). Because some...
متن کاملCarbohydrate composition of vesicular stomatitis virus.
Analysis by gas-liquid chromatography of the trimethylsilylated sugar residues of purified vesicular stomatitis virus grown in L cells or chick embryo cells revealed the presence in the whole virion of four hexoses (glucose, galactose, mannose, and fucose), two hexosamines (glucosamine and galactosamine), and 34 to 40% neuraminic acid. The isolated viral glycoprotein was devoid of galactosamine...
متن کاملAlteration of the Membrane Lipid Composition and Infectivity of Vesicular Stomatitis Virus
The cholesterol and phospholipid composition of the membrane of vesicular stomatitis (VS) virus was altered by growth in a sterol auxotroph Chinese hamster ovary (CHO MI) host cell and by infection of CHO MI and baby hamster kidney (BHK)-%l cells supplemented with fatty acids and dimethylethanolamine. VS virus released from infected CHO MI sterol auxotroph cells grown in delipidated serum had a...
متن کاملVesicular Stomatitis Virus–Based Vaccines against Lassa and Ebola Viruses
We demonstrated that previous vaccination with a vesicular stomatitis virus (VSV)-based Lassa virus vaccine does not alter protective efficacy of subsequent vaccination with a VSV-based Ebola virus vaccine. These findings demonstrate the utility of VSV-based vaccines against divergent viral pathogens, even when preexisting immunity to the vaccine vector is present.
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
ژورنال
عنوان ژورنال: Journal of Virology
سال: 1971
ISSN: 0022-538X,1098-5514
DOI: 10.1128/jvi.7.1.59-70.1971